作者：刘静、葛小龙、欧阳春晖、王冬旭、张晓琪、梁杰、朱伟明、曹倩、中国IBD精英联盟
医院单位：
浙江大学医学院邵逸夫医院炎症性肠病中心；浙江大学医学院邵逸夫医院消化内科；浙江大学医学院邵逸夫医院普外科；中南大学湘雅二医院消化内科；中国医科大学盛京医院消化内科；南京大学医学院南京鼓楼医院消化内科；第四军医大学医学院西京医院消化内科；南京大学金陵医院普外科。
© 2022 克罗恩和结肠炎基金会。牛津大学出版社代表克罗恩和结肠炎基金会出版。
摘要
背景：炎症性肠病 (IBD) 患者普遍存在营养不良。亚洲 IBD 患者的营养状况很少被调查。我们评估了中国 IBD 患者营养不良的患病率和危险因素、营养支持的使用以及与营养不良相关的社会心理状况。
方法：
在这项横断面研究中，对来自 43 家三级转诊医院的溃疡性结肠炎 (UC) 和克罗恩病 (CD) 患者进行了营养不良和营养缺乏症筛查。记录营养支持的使用。通过主观问卷评估社会心理状况。分析与营养不良相关的因素，并使用多元回归确定营养不良的独立预测因子。
结果：
我们招募了 1013 名患者，中位年龄为 35.0 岁，其中 58.5% 患有 CD，所有患者中男性占 61.4%。总体而言，49.5% (501) 的患者被诊断为营养不良，包括 57.0% 的 CD 患者、38.8% 的 UC 患者和 44.1% 的静止或轻度活动性疾病患者。尽管没有营养不良，但营养缺乏仍然很普遍。营养不良与不良社会心理状况相关，包括社会支持减少、压力感知增加和生活质量受损。中度至重度疾病活动和广泛疾病是营养不良的两个独立危险因素。总共有41.6%的患者接受了营养支持，有危险因素的患者更有可能接受营养支持。
结论：营养不良在中国 IBD 患者中非常普遍，并与不良后果相关。营养不良筛查和早期营养支持是 IBD 护理的重要组成部分。
关键词：炎症性肠病；营养不良；营养支持。
PMID: 34984471
DOI: 10.1093/ibd/izab345
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